This presentation outlines current thinking and emerging best practice for programme and project selection and prioritisation. It refers to initiatives managed by the UK Office of Government Commerce; ProgM (the Association for Project Management and British Computer Society's Special Interest Group in Programme Management); the Project Management Institute and the Association for Project Management. This emerging best-practice approach provides processes for selecting and prioritising programmes on the basis of their required investments in terms of money and resources balanced with the expected financial and non-financial benefits. Examples are drawn from both the public and commercial sectors where IT departments are playing a key role in developing a rational approach to this topic.