Disruptive technologies are those that enter the market that have, over time, an opportunity to displace the technologies of the market leaders. The criterion used usually is by cost, even though performance of the disruptive technology might not be as good as those that exist. Emerging health technologies that have the potential to be disruptive are identified and, as an example, applications of XML-mediated open source software are used as a case study. Messages taken from the disruptive process are discussed in terms of its impact and value on the innovation cycle.